In this report, the Global Endoscopic Clips Market has been segmented by Material, Size, Application, End User and Geography.

Global Endoscopic Clips Market, Segmentation by Material

The Global Endoscopic Clips Market has been segmented by Material into Titanium Clips, Nitinol Clips, Polypropylene Clips, Polyethylene Clips and Polyglycolic Acid Clips.

Titanium Clips
Titanium clips lead the global endoscopic clips market with a share of about 42%. Their high tensile strength, biocompatibility, and radiographic visibility make them the preferred choice for endoscopic bleeding control, perforation repair, and polypectomy site closure. Common in gastrointestinal endoscopy, titanium clips are the standard in both diagnostic and therapeutic applications.

Nitinol Clips
Nitinol clips account for approximately 26% of the market and are known for their shape-memory properties, allowing them to adapt precisely to tissue movement. They provide reliable performance in dynamic organs such as the esophagus and colon, and are frequently chosen for recurrent bleeding sites and mucosal fold stabilization.

Polypropylene Clips
Polypropylene clips hold about 12% of the market. These lightweight, non-metallic clips are favored for cost-sensitive procedures and short-term use, such as training simulations or low-pressure bleeding management. Their flexibility and affordability ensure continued demand in low-resource settings.

Polyethylene Clips
Polyethylene clips, comprising 10% of the market, are used for temporary tissue approximation in minor endoscopic procedures. Their chemical inertness and ease of application make them useful in non-critical hemostatic interventions, especially in ambulatory and rural care units.

Polyglycolic Acid Clips
Polyglycolic acid (PGA) clips also represent about 10% of the market. These bioabsorbable clips eliminate the need for retrieval post-procedure, making them ideal for mucosal defect closures, endoscopic submucosal dissections (ESD), and early cancer resections. Their degradability aligns with the growing trend toward minimally invasive and post-operative complication-reducing tools.

Global Endoscopic Clips Market, Segmentation by Size

The Global Endoscopic Clips Market has been segmented by Size into Small Size Clips, Medium Size Clips, Large Size Clips, and XL Size Clips.

Small Size Clips
Small size endoscopic clips make up about 35% of the market and are primarily used for targeted tissue closure, particularly in small mucosal tears, biopsy sites, and low-pressure bleeding points. Their compact size allows for precise placement in narrow or sensitive anatomical regions, making them especially valuable in pediatric endoscopy and upper GI procedures.

Medium Size Clips
Medium size clips account for roughly 33% of the market and are widely regarded as the standard size for most general endoscopic procedures. These clips provide a balanced mix of flexibility and retention force, suitable for routine tasks such as polypectomy site closure, minor GI bleeding, and tissue marking.

Large Size Clips
Large size endoscopic clips represent about 20% of global use. These clips are engineered for high-tension sites, capable of closing larger mucosal defects and active hemorrhagic lesions. They are frequently used in colonoscopies, endoscopic mucosal resections (EMR), and gastric ulcer repairs.

XL Size Clips
XL size clips comprise around 12% of the market and are designed for specialized therapeutic endoscopy. With a wider span and higher holding strength, they are preferred for complex gastrointestinal repairs, such as large mucosal lacerations and anatomically challenging closures that demand advanced clip mechanics.

Global Endoscopic Clips Market, Segmentation by Application

The Global Endoscopic Clips Market has been segmented by Application into Hemostasis, Endoscopic Marking, and Others.

Hemostasis
Hemostasis is the primary driver of the global endoscopic clips market, accounting for nearly 64% of total usage. Endoscopic clips play a critical role in controlling acute GI bleeding, particularly in conditions such as bleeding ulcers, post-procedural hemorrhages, and Dieulafoy’s lesions. The immediate mechanical closure provided by clips makes them essential for emergency bleeding control in both upper and lower GI endoscopy.

Endoscopic Marking
Endoscopic marking contributes about 21% of the market and is vital for lesion localization, especially when planning follow-up surgeries, endoscopic resections, or targeted imaging. These clips are radiopaque, making them easily visible in CT scans, fluoroscopy, and intraoperative imaging—thus improving the precision of minimally invasive treatments.

Others
The Others category, representing around 15% of global use, includes tissue approximation, perforation closure, and mucosal defect repair following procedures like EMR and ESD. As non-surgical endoscopic therapies expand, particularly in early gastrointestinal cancer management, the demand for advanced clipping applications continues to rise.

Global Endoscopic Clips Market, Segmentation by End User

The Global Endoscopic Clips Market has been segmented by End User into Hospitals, Ambulatory Surgical Centers, and Others.

Hospitals
Hospitals lead the global endoscopic clips market, accounting for approximately 64% of total usage. As the primary centers for complex gastrointestinal procedures, hospitals use endoscopic clips for emergency hemostasis, tissue repair, and post-resection closures. Their integration with 24/7 care teams, ICUs, and interventional endoscopy departments ensures consistent and high-volume clip deployment across routine and critical cases.

Ambulatory Surgical Centers
Ambulatory Surgical Centers (ASCs) represent about 24% of the market and are key players in delivering minimally invasive gastrointestinal care. With a focus on cost-effective procedures and high patient throughput, ASCs are expanding their use of endoscopic clips for routine hemostasis, mucosal tagging, and post-polypectomy care. Their growth is being fueled by rising demand for outpatient endoscopy services.

Others
The Others segment, comprising roughly 12%, includes academic centers, GI research labs, and independent specialty clinics. These institutions use endoscopic clips for clinical training, pilot studies, and low-risk therapeutic interventions, particularly in teaching hospitals and innovation hubs exploring advanced clip designs and deployment techniques.

Global Endoscopic Clips Market, Segmentation by Geography

In this report, the Global Endoscopic Clips Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East & Africa and Latin America.

Global Endoscopic Clips Market Share (%), by Geographical Region, 2024

North America
North America dominates the global endoscopic clips market, accounting for about 39% of the total share. The region’s leadership is fueled by high adoption of GI endoscopy procedures, increasing demand for minimally invasive hemostasis solutions, and strong reimbursement frameworks. The U.S. in particular benefits from a mature endoscopy infrastructure and the presence of leading manufacturers driving product innovation.

Europe
Europe contributes approximately 26% to the market, led by countries such as Germany, France, and the UK. The region is known for its robust clinical guidelines, emphasis on early gastrointestinal cancer detection, and widespread implementation of advanced endoscopic interventions. Growth is also supported by government-funded healthcare systems and research-led product development.

Asia Pacific
Asia Pacific holds roughly 23% of the market and is experiencing the fastest growth rate globally. Rapid urbanization, rising cases of gastric and colorectal conditions, and improved access to endoscopic care are driving demand. Investment in training programs, increasing patient awareness, and growth in private healthcare providers are further boosting adoption across the region.

Middle East & Africa
Middle East & Africa accounts for about 7% of global market share. Expansion in this region is supported by increasing investments in medical infrastructure, particularly in countries such as the UAE and Saudi Arabia. As demand for minimally invasive GI treatments rises, more healthcare facilities are incorporating endoscopic clipping systems into their standard protocols.

Latin America
Latin America makes up approximately 5% of the market, with Brazil and Mexico leading in terms of procedure volumes. The region is witnessing growth through the expansion of colorectal screening programs, improvements in hospital endoscopy units, and increasing collaboration between public and private healthcare sectors to improve access to GI therapeutics.