Global Post-Operative Pain Management Market Growth, Share, Size, Trends and Forecast (2025 - 2031)

By Product Type;

Analgesics, Local Anesthetics, Opioids, Nonsteroidal Anti-Inflammatory Drugs, and Adjuvants

By Administration Route;

Oral, Intravenous, Transdermal, Regional, and Subcutaneous

By Application;

Orthopedic Surgery, Cardiothoracic Surgery, General Surgery, Gynecological Surgery, and Urological Surgery

By End User;

Hospitals, Ambulatory Surgical Centers, and Home Care Settings

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn140728757 Published Date: May, 2025 Updated Date: June, 2025

Post-Operative Pain Management Market Overview

Post-Operative Pain Management Market (USD Million)

Post-Operative Pain Management Market was valued at USD 21,328.95 million in the year 2024. The size of this market is expected to increase to USD 32,283.25 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 6.1%.


Global Post-Operative Pain Management Market Growth, Share, Size, Trends and Forecast

*Market size in USD million

CAGR 6.1 %


Study Period2025 - 2031
Base Year2024
CAGR (%)6.1 %
Market Size (2024)USD 21,328.95 Million
Market Size (2031)USD 32,283.25 Million
Market ConcentrationMedium
Report Pages372
21,328.95
2024
32,283.25
2031

Major Players

  • Teva Pharmaceutical Industries Ltd
  • Eli Lilly
  • Pfizer
  • Johnson & Johnson
  • Purdue Pharma

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

Global Post-Operative Pain Management Market

Fragmented - Highly competitive market without dominant players


The Post-Operative Pain Management Market is expanding rapidly, driven by the increasing number of surgeries performed worldwide. Effective pain control is essential for enhancing recovery outcomes and minimizing post-surgical complications. Approximately 60% of surgical patients experience moderate to severe pain, underscoring the demand for innovative pain management solutions. This growth is further supported by the rising emphasis on patient-centric care and improving overall quality of life for patients.

Rising Preference for Non-Opioid Therapies
With growing concerns over opioid dependence and side effects, the market is witnessing a shift toward non-opioid therapies. Nearly 40% of healthcare professionals now prefer using alternatives like local anesthetics, nerve blocks, and multi-modal analgesia to manage post-operative pain. This trend reflects the increasing focus on patient safety and the need for effective, low-risk pain relief options.

Technological Innovations in Pain Management
Technological advancements are transforming the post-operative pain management landscape, with devices such as infusion pumps, nerve stimulators, and cryotherapy systems gaining traction. Nearly 30% of newly developed pain management products emphasize patient-controlled analgesia, aligning with the demand for personalized and precise treatment options that empower patients to control their pain effectively.

Supportive Regulatory Initiatives
Government support and favorable regulatory frameworks are significantly boosting market growth. More than 35% of healthcare programs globally now incorporate structured pain management protocols, reflecting a commitment to improving patient care and reducing the economic burden of untreated pain. These measures aim to reduce hospital readmissions and enhance patient outcomes, making effective pain management a priority in modern healthcare.

Future Market Potential
As a critical component of post-surgical recovery, the Post-Operative Pain Management Market is set for steady expansion. Continuous clinical research, rising patient awareness, and the shift toward value-based healthcare are expected to create significant growth opportunities, encouraging innovation and improved patient outcomes in the coming years.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Product Type
    2. Market Snapshot, By Administration Route
    3. Market Snapshot, By Application
    4. Market Snapshot, By End User
    5. Market Snapshot, By Region
  4. Post-Operative Pain Management Market Dynamics
    1. Drivers, Restraints and Opportunities
      1. Drivers
        1. Increasing Surgical Procedures
        2. Growing Awareness and Emphasis on Patient Comfort
        3. Technological Advancements in Pain Management
      2. Restraints
        1. Concerns Over Opioid Misuse and Addiction
        2. Limited Access to Advanced Pain Management Therapies
        3. Reimbursement Challenges
      3. Opportunities
        1. Focus on Multimodal Pain Management
        2. Advancements in Minimally Invasive Techniques
        3. Rise of Digital Health Solutions
    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry
  5. Market Segmentation
    1. Post-Operative Pain Management Market, By Product Type Type, 2021 - 2031 (USD Million)
      1. Analgesics
      2. Local Anesthetics
      3. Opioids
      4. Nonsteroidal Anti-Inflammatory Drugs
      5. Adjuvants
    2. Post-Operative Pain Management Market, By Administration Route, 2021 - 2031 (USD Million)
      1. Oral
      2. Intravenous
      3. Transdermal
      4. Regional
      5. Subcutaneous
    3. Post-Operative Pain Management Market, By Application, 2021 - 2031 (USD Million)
      1. Orthopedic Surgery
      2. Cardiothoracic Surgery
      3. General Surgery
      4. Gynecological Surgery
      5. Urological Surgery
    4. Post-Operative Pain Management Market, By End User, 2021 - 2031 (USD Million)
      1. Hospitals
      2. Ambulatory Surgical Centers
      3. Home Care Setting
    5. Post-Operative Pain Management Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles
      1. Pfizer Inc.
      2. Johnson & Johnson
      3. AbbVie Inc.
      4. Teva Pharmaceutical Industries Ltd.
      5. Eli Lilly and Company
      6. GlaxoSmithKline plc (GSK)
      7. Endo Pharmaceuticals Inc.
      8. Mallinckrodt Pharmaceuticals
      9. Pacira BioSciences, Inc.
      10. Baxter International Inc.
  7. Analyst Views
  8. Future Outlook of the Market