Global Protein Detection and Quantification Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Technology;
Colorimetric Assays, Immunological Methods, Chromatography, Mass Spectrometry, Spectroscopy Instruments, and OthersBy Product;
Consumables, Instruments, and ServicesBy Application;
Drug Discovery & Development, Clinical Diagnosis, and OthersBy End Use;
Academic Research Institutes, Biotechnology & Pharmaceutical Companies, Contract Research Organizations, and OthersBy Geography;
North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)Protein Detection and Quantification Market Overview
Protein Detection and Quantification Market (USD Million)
Protein Detection and Quantification Market was valued at USD 2,756.39 million in the year 2024. The size of this market is expected to increase to USD 4,608.84 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 7.6%.
Global Protein Detection and Quantification Market Growth, Share, Size, Trends and Forecast
*Market size in USD million
CAGR 7.6 %
Study Period | 2025 - 2031 |
---|---|
Base Year | 2024 |
CAGR (%) | 7.6 % |
Market Size (2024) | USD 2,756.39 Million |
Market Size (2031) | USD 4,608.84 Million |
Market Concentration | Medium |
Report Pages | 382 |
Major Players
- Thermo Fisher Scientific Inc
- Merck KGaA
- Bio-Rad Laboratories, Inc
- Agilent Technologies, Inc
- PerkinElmer, Inc
- GE Healthcare
- Bruker Corporation
- Bio-Techne Corporation
- Qiagen N.V
- Promega Corporation
Market Concentration
Consolidated - Market dominated by 1 - 5 major players
Global Protein Detection and Quantification Market
Fragmented - Highly competitive market without dominant players
The Protein Detection and Quantification Market is experiencing significant expansion due to increasing demand for precise protein-level analysis in biological and clinical research. The rise in proteomics applications and growing reliance on targeted protein-based diagnostics have driven the demand for more accurate and sensitive quantification technologies. This market has seen an increase of over 15% in adoption of high-throughput analytical tools, reflecting the shift toward advanced and automated workflows.
Advancements in mass spectrometry, fluorescence-based assays, and label-free detection systems have enhanced sensitivity and scalability in protein quantification. These technologies now account for more than 40% of usage in clinical proteomics workflows. Innovations in microfluidics and single-cell analysis have further elevated detection precision, improving reproducibility rates by nearly 30% compared to traditional methods.
Rising Research and Diagnostic Applications
With protein biomarkers increasingly used in diagnostics and drug discovery, the market has observed a 20% surge in demand for multiplexed assays and quantification platforms. These tools enable simultaneous analysis of multiple proteins, accelerating research timelines and enhancing clinical decision-making. Additionally, academic and commercial laboratories are expanding their investments in proteomic profiling.
Growing Emphasis on Personalized Medicine
The growing focus on personalized and precision medicine has contributed to a rise in protein analysis tools adoption by over 18%. Integration of these tools into therapeutic decision-making and treatment monitoring has bolstered their value in clinical settings. Protein quantification supports the development of targeted therapies, improving treatment outcomes and supporting stratified patient care strategies.
Increased Funding and Strategic Collaborations
The market is witnessing an uptick in research funding, partnerships, and licensing agreements among biotech firms and academic institutions. These collaborations have increased by approximately 25%, aiming to advance the development of novel platforms and expand assay portfolios. Government initiatives supporting molecular diagnostics and proteomic research continue to create lucrative opportunities for industry expansion.
Protein Detection and Quantification Market Recent Developments
-
February 2023: Charles River Laboratories International, Inc. launched its first Enzyme-Linked Immunosorbent Assay (ELISA) Kit. It is to detect and quantify residual host cell proteins (HCP) in CHO-based biotherapeutics.
-
April 2022: PerkinElmer, Inc. launched two ready-to-use HTRF and AlphaLISA no-wash assay kits. It is designed to quickly and easily detect and quantify CHO HCP (Host Cell Protein) impurities during biopharmaceutical manufacturing.
Protein Detection and bio-rad protein assay Quantification Market Segment Analysis
In this report, the Protein Detection and bio-rad protein assay Quantification Market has been segmented by Technology, Product, Application, End Use and Geography.
Protein Detection and Quantification Market, Segmentation by Technology
The Protein Detection and Quantification Market has been segmented by Technology into Colorimetric Assays, Immunological Methods, Chromatography, Mass Spectrometry, Spectroscopy Instruments and Others.
Colorimetric Assays
Colorimetric assays account for nearly 28% of the market due to their simplicity, cost-effectiveness, and rapid protein detection capabilities. These assays are widely used in clinical diagnostics and academic research.
Immunological Methods
Immunological methods, such as ELISA and Western blotting, represent around 25% of the market. These techniques are favored for their high specificity and sensitivity in protein quantification and biomarker validation.
Chromatography
Chromatography holds a market share of approximately 18%. Techniques like HPLC are essential for protein purification and complex sample separation, particularly in pharmaceutical and proteomics applications.
Mass Spectrometry
Mass spectrometry contributes about 15% to the market, offering precise identification and quantitative analysis of proteins. It is widely applied in drug discovery and clinical proteomics.
Spectroscopy Instruments
Spectroscopy instruments comprise roughly 10% of the market. They are instrumental in evaluating protein structure, stability, and binding interactions using techniques like UV-Vis and IR spectroscopy.
Others
The remaining 4% includes emerging and hybrid technologies such as microfluidics and label-free detection systems. These are gradually gaining attention for their real-time analysis capabilities.
Protein Detection and Quantification Market, Segmentation by Product
The Protein Detection and Quantification Market has been segmented by Product into Consumables, Instruments and Services.
Consumables
Consumables dominate the market with a share of around 50%, driven by the high demand for reagents, assay kits, and antibodies. These are essential for conducting a wide range of protein analysis procedures in both research and clinical settings.
Instruments
Instruments contribute approximately 30% to the market, encompassing spectrophotometers, mass spectrometers, and chromatography systems. Their ability to deliver accurate, high-throughput protein quantification supports their growing adoption in advanced laboratories.
Services
Services account for nearly 20% of the market, including contract testing, custom assay development, and data analysis. Outsourcing these services is gaining popularity among biotech firms and academic institutions for cost and time efficiency.
Protein Detection and Quantification Market, Segmentation by Application
The Protein Detection and Quantification Market has been segmented by Application into Drug Discovery & Development, Clinical Diagnosis and Others.
Academic Research Institutes
Academic research institutes contribute to around 35% of the market. These institutions rely heavily on protein quantification tools for basic science research, disease mechanism studies, and biomarker discovery.
Biotechnology & Pharmaceutical Companies
This segment accounts for nearly 40% of the market, driven by high demand for protein analysis during drug development, quality control, and clinical trials. The need for precise quantification enhances investment in advanced instruments and services.
Contract Research Organizations
Contract research organizations (CROs) hold a share of approximately 15%, offering outsourced protein assay services to pharma and biotech companies. Their role in supporting cost-effective, scalable R&D is steadily expanding.
Others
The remaining 10% includes clinical labs, diagnostic centers, and government research agencies. These users require reliable tools for routine diagnostics, therapeutic monitoring, and public health studies.
Protein Detection and Quantification Market, Segmentation by End Use
The Protein Detection and Quantification Market has been segmented by End Use into Academic Research Institutes, Biotechnology & Pharmaceutical Companies, Contract Research Organizations and Others.
Academic Research Institutes
Academic research institutes contribute to around 35% of the market. These institutions rely heavily on protein quantification tools for basic science research, disease mechanism studies, and biomarker discovery.
Biotechnology & Pharmaceutical Companies
This segment accounts for nearly 40% of the market, driven by high demand for protein analysis during drug development, quality control, and clinical trials. The need for precise quantification enhances investment in advanced instruments and services.
Contract Research Organizations
Contract research organizations (CROs) hold a share of approximately 15%, offering outsourced protein assay services to pharma and biotech companies. Their role in supporting cost-effective, scalable R&D is steadily expanding.
Others
The remaining 10% includes clinical labs, diagnostic centers, and government research agencies. These users require reliable tools for routine diagnostics, therapeutic monitoring, and public health studies.
Protein Detection and Quantification Market, Segmentation by Geography
In this report, the Protein Detection and Quantification Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Regions and Countries Analyzed in this Report
Protein Detection and Quantification Market Share (%), by Geographical Region
North America
North America holds the largest share of the market at approximately 38%, driven by the presence of major biotech firms, strong investments in protein research, and a robust healthcare infrastructure supporting advanced diagnostics.
Europe
Europe accounts for around 27% of the market, fueled by continuous R&D in proteomics, government-funded projects, and a high adoption rate of innovative diagnostic solutions across the region.
Asia Pacific
Asia Pacific holds a market share of nearly 22%, with growth driven by expanding biopharmaceutical industries, rising healthcare spending, and increased emphasis on clinical research in countries like China, India, and Japan.
Middle East and Africa
This region contributes about 7% to the market, benefiting from growing investments in healthcare infrastructure and the adoption of modern protein analysis technologies in select countries.
Latin America
Latin America represents approximately 6% of the market. Rising awareness of clinical diagnostics and expanding biotech capabilities in Brazil and Mexico are key contributors to regional market growth.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Protein Detection and Quantification Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunities Analysis
Drivers
- Technological advancements
- Increasing research in proteomics
- Growing demand for personalized medicine
-
Rising prevalence of chronic diseases - The growing prevalence of chronic diseases such as cancer, diabetes, cardiovascular conditions, and neurodegenerative disorders is a major driver of the global protein detection and quantification market. These diseases often involve complex biological processes that require precise analysis of protein expression, concentration, and function for early diagnosis, monitoring, and treatment planning. As the burden of chronic conditions escalates worldwide, the demand for sensitive and accurate protein detection technologies continues to rise across clinical and research settings.
Protein detection plays a crucial role in understanding disease progression and identifying therapeutic targets, especially in the era of personalized and precision medicine. Advances in proteomics and biomarker discovery are further amplifying the need for robust quantification tools, supporting drug development and translational research. With the increasing focus on preventive healthcare and early intervention, protein-based assays and analytical platforms are becoming indispensable in managing long-term illnesses and improving patient outcomes.
Restraints
- High cost of instruments
- Lack of skilled professionals
- Stringent regulatory requirements
-
Limited awareness in developing regions - Limited awareness in developing regions serves as a significant restraint to the growth of the global protein detection and quantification market. In many low- and middle-income countries, the understanding of advanced molecular diagnostics and proteomic applications remains low among healthcare professionals and patients. This lack of awareness affects the adoption of protein-based analytical tools, despite their critical role in early disease detection, treatment monitoring, and biomedical research.
The absence of widespread educational initiatives and limited access to specialized training hinder the implementation of modern diagnostic technologies. Without adequate knowledge about the benefits of protein quantification in clinical decision-making, healthcare systems in these regions continue to rely on conventional diagnostic methods. Overcoming this challenge requires targeted outreach, capacity-building programs, and investment in diagnostic education to bridge the gap and unlock the full potential of protein-based technologies in underserved markets.
Opportunities
- Expansion in emerging markets
- Development of novel detection methods
- Collaborations and partnerships
-
Integration of artificial intelligence - The integration of artificial intelligence (AI) offers a major opportunity to advance the protein detection and quantification market by improving the speed, accuracy, and efficiency of complex data analysis. AI algorithms can automate protein analysis workflows, interpret large datasets from proteomic studies, and enhance the identification of biomarker patterns and disease indicators. This technology reduces manual errors, ensures consistency, and supports high-throughput research in diagnostics and drug development.
AI also enables the creation of predictive models that link protein expression to disease progression and treatment response, making protein-based diagnostics more actionable in clinical practice. By lowering operational costs and simplifying complex analyses, AI integration is especially beneficial for expanding access to advanced diagnostic tools in both centralized laboratories and decentralized healthcare environments. This growing adoption is expected to reshape the future of personalized medicine and molecular diagnostics.
Competitive Landscape Analysis
Key players in Global Protein Detection and Quantification Market include:
- Thermo Fisher Scientific Inc
- Merck KGaA
- Bio-Rad Laboratories, Inc
- Agilent Technologies, Inc
- PerkinElmer, Inc
- GE Healthcare
- Bruker Corporation
- Bio-Techne Corporation
- Qiagen N.V
- Promega Corporation
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Market Share Analysis
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Technology
- Market Snapshot, By Product
- Market Snapshot, By Application
- Market Snapshot, By End Use
- Market Snapshot, By Region
- Protein Detection and Quantification Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Technological advancements
- Increasing research in proteomics
- Growing demand for personalized medicine
- Rising prevalence of chronic diseases
- Restraints
- High cost of instruments
- Lack of skilled professionals
- Stringent regulatory requirements
- Limited awareness in developing regions
- Opportunities
- Expansion in emerging markets
- Development of novel detection methods
- Collaborations and partnerships
- Integration of artificial intelligence
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Protein Detection and Quantification Market, By Technology, 2021 - 2031 (USD Million)
- Colorimetric Assays
- Immunological Methods
- Chromatography
- Mass Spectrometry
- Spectroscopy Instruments
- Others
- Protein Detection and Quantification Market, By Product, 2021 - 2031 (USD Million)
- Consumables
- Instruments
- Services
- Protein Detection and Quantification Market, By Application, 2021 - 2031 (USD Million)
- Drug Discovery & Development
- Clinical Diagnosis
- Others
- Protein Detection and Quantification Market, By End Use, 2021 - 2031 (USD Million)
- Academic Research Institutes
- Biotechnology & Pharmaceutical Companies
- Contract Research Organizations
- Others
- Protein Detection and Quantification Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Competitive Landscape
- Company Profiles
- Thermo Fisher Scientific Inc
- Merck KGaA
- Bio-Rad Laboratories, Inc
- Agilent Technologies, Inc
- PerkinElmer, Inc
- GE Healthcare
- Bruker Corporation
- Bio-Techne Corporation
- Qiagen N.V
- Promega Corporation
- Company Profiles
- Protein Detection and Quantification Market, By Technology, 2021 - 2031 (USD Million)
- Analyst Views
- Future Outlook of the Market