Global Pulmonary Hypertension Market Growth, Share, Size, Trends and Forecast (2025 - 2031)

By Formulation;

Oral, Injection, and Inhalation

By Mechanism of Action;

Soluble Guanylate Cyclase Stimulators, Endothelin Receptor Antagonist, Prostacyclin Analogues, and Phosphodiesterase Inhibitors

By Geography;

North America, Europe, Asia Pacific, Middle East & Africa, and Latin America - Report Timeline (2021 - 2031)
Report ID: Rn577763157 Published Date: May, 2025 Updated Date: June, 2025

Pulmonary Hypertension Market Overview

Pulmonary Hypertension Market ( USD Million)

Pulmonary Hypertension Market was valued at USD 8,222.83 million in the year 2024. The size of this market is expected to increase to USD 11,890.33 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 5.4%.


Global Pulmonary Hypertension Market Growth, Share, Size, Trends and Forecast

*Market size in USD million

CAGR 5.4 %


Study Period2025 - 2031
Base Year2024
CAGR (%)5.4 %
Market Size (2024)USD 8,222.83 Million
Market Size (2031)USD 11,890.33 Million
Market ConcentrationMedium
Report Pages353
8,222.83
2024
11,890.33
2031

Major Players

  • Actelion Pharmaceuticals
  • United Therapeutics
  • GSK and Bayer Healthcare

Market Concentration

Consolidated - Market dominated by 1 - 5 major players

Global Pulmonary Hypertension Market

Fragmented - Highly competitive market without dominant players


The Pulmonary Hypertension Market is expanding steadily, driven by the rising prevalence of pulmonary vascular disorders and associated cardiac issues. This chronic condition, marked by high pressure in the pulmonary arteries, affects nearly 30% of patients with pre-existing heart or lung diseases. The increasing incidence of COPD and left-sided heart dysfunction is contributing to the growing demand for more advanced and targeted treatment solutions.

Widespread Use of Targeted Drug Therapies
Modern treatment strategies are increasingly centered around targeted drug classes, including endothelin receptor antagonists and phosphodiesterase-5 inhibitors. These medications now represent about 55% of therapies prescribed for managing pulmonary hypertension. With continuous advancements in disease biology, newer therapies are being designed to provide precise symptom control, improved hemodynamics, and enhanced patient outcomes.

Emphasis on Early Detection and Diagnosis
Early diagnosis has become a crucial focus, as timely intervention significantly improves prognosis. Currently, over 40% of cases are being diagnosed at earlier stages, owing to better screening programs and clinical awareness. Enhanced use of imaging tools and biomarker diagnostics is helping physicians detect the disease sooner, thereby increasing the chances of successful treatment and reducing long-term complications.

Regulatory Push and Healthcare Initiatives
Supportive policies and investments from healthcare authorities are further fueling market expansion. Over 45% of rare disease clinical guidelines now include dedicated treatment pathways for pulmonary hypertension, showcasing the condition’s growing priority. These policy measures are encouraging research and facilitating broader access to effective therapies, strengthening the outlook for this critical treatment domain.

  1. Introduction
    1. Research Objectives and Assumptions
    2. Research Methodology
    3. Abbreviations
  2. Market Definition & Study Scope
  3. Executive Summary
    1. Market Snapshot, By Formulation
    2. Market Snapshot, By Mechanism of Action
    3. Market Snapshot, By Region
  4. Pulmonary Hypertension Market Dynamics
    1. Drivers, Restraints and OpportunitiesPEST Analysis
      1. Drivers
        1. Increasing Prevalence of Pulmonary Hypertension
        2. Advancements in Diagnostic Technologies
        3. Growing Awareness and Education Initiatives
      2. Restraints
        1. High Cost of Treatment
        2. Lack of Early Symptoms and Misdiagnosis
        3. Side Effects of Available Treatments
      3. Opportunities
        1. Emerging Therapies and Drug Approvals
        2. Improved Patient Monitoring Technologies
        3. Expanding Access to Treatment in Emerging Markets
    2. PEST Analysis
      1. Political Analysis
      2. Economic Analysis
      3. Social Analysis
      4. Technological Analysis
    3. Porter's Analysis
      1. Bargaining Power of Suppliers
      2. Bargaining Power of Buyers
      3. Threat of Substitutes
      4. Threat of New Entrants
      5. Competitive Rivalry
  5. Market Segmentation
    1. Pulmonary Hypertension Market, By Formulation, 2021 - 2031 (USD Million)
      1. Oral
      2. Injection
      3. Inhalation
    2. Pulmonary Hypertension Market, By Mechanism of Action, 2021 - 2031 (USD Million)
      1. Soluble Guanylate Cyclase Stimulators
      2. Endothelin Receptor Antagonist
      3. Prostacyclin Analogues
      4. Phosphodiesterase Inhibitors
    3. Pulmonary Hypertension Market, By Geography, 2021 - 2031 (USD Million)
      1. North America
        1. United States
        2. Canada
      2. Europe
        1. Germany
        2. United Kingdom
        3. France
        4. Italy
        5. Spain
        6. Nordic
        7. Benelux
        8. Rest of Europe
      3. Asia Pacific
        1. Japan
        2. China
        3. India
        4. Australia & New Zealand
        5. South Korea
        6. ASEAN (Association of South East Asian Countries)
        7. Rest of Asia Pacific
      4. Middle East & Africa
        1. GCC
        2. Israel
        3. South Africa
        4. Rest of Middle East & Africa
      5. Latin America
        1. Brazil
        2. Mexico
        3. Argentina
        4. Rest of Latin America
  6. Competitive Landscape
    1. Company Profiles:
      1. Johnson & Johnson
      2. United Therapeutics Corporation
      3. Bayer AG
      4. GlaxoSmithKline plc
      5. Gilead Sciences, Inc.
      6. Pfizer Inc.
      7. Bristol Myers Squibb
      8. Merck & Co., Inc.
      9. AbbVie Inc.
      10. Novartis AG
  7. Analyst Views
  8. Future Outlook of the Market